In the 2004 film, Eternal Sunshine of the Spotless Mind, a heartbroken man played by Jim Carrey undergoes an experimental treatment to erase memories of his ex-girlfriend, played by Kate Winslet, following their painful breakup. When the film came out, using drugs or other technologies to meddle with memory, especially as a way of healing from a traumatic relationship, was not exactly feasible in the real world.
- Nautilus